Silicified Microcrystalline Cellulose | Product

Silicified Microcrystalline
Cellulose

RITECEL SMCC, manufactured by Cellutech Pharma, exhibits enhanced physical properties including true density, Hauser ratio, porosity, ejection force, and specific surface area. These improvements are attributed to the addition of fumed silica, which enhances the overall performance of the SMCC. However, it should be noted that the bulk and tap densities of RITECEL SMCC are reduced due to the amorphous and lightweight nature of the fumed silica component. This unique combination of properties makes RITECEL SMCC a valuable excipient for pharmaceutical formulations requiring optimized flowability, compressibility, and drug delivery characteristics.

Product Data Sheet

SMCC Standard Types

RITECEL SMCC has increased physical properties in true density, Hauser ratio, porosity, ejection force and specific surface area.
Other properties such as bulk and tap densities are reduced due to fumed silica's amorphous and light character.

Grade	Particle Size Distribution					LOD** %	Bulk Density* g/CC
	Retention Method (Sieve Analysis)*		By Laser Diffraction Method*
	60# %	200# %	D10 (µm)	D50 (µm)	D90 (µm)
RITECEL® SMCC 50	NMT 1.0	NMT 30	15-30	45-80	100-180	3.0-5.0	0.27-0.35
RITECEL® SMCC 90	NMT 8.0	NLT 45	20-50	90-150	190-300	3.0-5.0	0.25-0.38
RITECEL® SMCC 90 HD	NMT 8.0	NLT 45	20-70	90-160	160-320	3.0-5.0	0.35-0.50

NMT: Not More ThanNLT: Not Less Than*: Customize as per customer requirements.**: More restrictive than a compendium.

Unique Features of RITECEL® SMCC

Angle
of Repose

Customized
Bulk Density

Excellent
Flowability

Better
Compressibility

Low
Moisture

Technical Specification of SMCC

Test	Specification
Description	White or almost white, very fine to moderately fine powder. It is a free-flowing material.
Solubility	Slightly soluble in sodium hydroxide solution (1 in 20); practically insoluble in water, in acetone, in ethanol, in toluene, and in diluted acid.
Identification
Test-A (IR Absorption)	Should be comply
Test-B	The substance takes on a violet-blue color should be produced.
Test-C	A deep yellow color is produced
Test-D(silica dispersion uniformity test)	NMT 0.02

Test	Specification
Impurities
Heavy Metals, µg/g	NMT 10
Specific Tests
Residue on Ignition, %	1.8 - 2.2
Conductivity, µS/cm	NMT 75
pH	5.0 - 7.5
Loss on Drying, %	NMT 7.0
Degree of Polymerization	NMT 350
Water Soluble Substances, %	NMT 0.25
Ether Soluble Substances, %	NMT 0.05

Benefits

Improved Compatibility
Enhanced Flow
Less sensitive to lubrication
Dust-reduced Handling in production.
A high degree of Brightness
Five times greater specific surface area than Microcrystalline cellulose.
Improved blending properties.
Increase Production rate

Rapid formulation development
Dust-Free Handling
Excellent Flow
Improved compatibility, leading to more robust tablets.
Smaller tablet size
Short disintegration time.
Minimize other excipient use.
Improve mixing character

Application Guide on each type of

RITECEL® SMCC

Type	Main Application
RITECEL® SMCC 50	Fine standard SMCC grade, recommended in Formulas that require optimal flow and consolidation exhibits the best disintegration time, indicating their superior ability to break down into smaller particles and dissolve evenly. And the best binder in our segment.	Direct compression tableting.
RITECEL® SMCC 90	Suitable in formulation for a balance of flow and compaction is required. recommended for Higher production speeds, and Rapid formulation development.	Direct compression tableting. Larger particles improve the flow and production rate.
RITECEL® SMCC 90HD	Same quality as grade SMCC 90, but increased bulk density and improved flow properties. Especially suited for high-speed tableting and processing high-density actives. Grater tablet weight, uniformity.	Direct compression tableting. Wet granulation. Potential for making smaller tablets.

Packing Details

HDPE / Paper Bags

25Kg / 20Kg

HDPE / Corrugated Drums

25Kg

Container

20 Ft. (Approx. Wt.) : 11,000 Kg
40 Ft. (Approx. Wt.) : 21,000 Kg